Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Tuberculoma
- Radiologic Findings
- 3. Chest radiograph shows ovoid single nodule in RML with fissural thickening. That nodule enlarged compared with chest radiograph taken in 4 years. On chest CT, 3 cm size mass containing dense calcification is located in RML abutting thickened major and minor fissures. Enhancement is not seen within that mass and there was no satellite nodule. Pathologic finding of PTNB specimen was chronic caseous granulomatous inflammation and mycobacterium tuberculosis PCR of tissue was positive.
- Brief Review
- 5. A pulmonary tuberculoma is one of the most common benign nodules and represents 5-24% of resected SPNs appearing a well-marginated smooth nodule or mass. The satellite lesions are in as many as 80% of cases. Diffuse or nodular calcification is found in 20-30% of the lesions. The presence of benign-looking calcification within the nodule, adjacent tree-in-bud lesions, or satellite nodules may help in differentiating tuberculomas from malignant nodules. The proposed mechanism is repeated extension of infection, subsequent a core of caseous necrosis surrounded by a mantle of epithelioid cells and multiple concentric layers of connective tissue. Most lesions are stable, but enlargement or the development of a new lesion should be considered either reactivation of tuberculosis or a malignancy.
- References
- 1.Goo JM, Im JG, Do KH, et al. Pulmonary tuberculomaevaluated by means of FDG PET: findings in 10 cases. Radiology 2000;216(1):117
2.Lee HS. Response of pulmonary tuberculomas to anti-tuberculous treatment. Eur Respir J 2004;23:452
3.Thoracic Imaing 2001: pulmonary tuberculosis volume 6, 2001 KSTR
- Keywords
- Lung, Infection, Bacterial infection,